Patrick Viatour, PharmD, PhD

Resident Faculty
Associate Professor

Dr. Viatour is interested in the mechanisms that govern cell division during episodes of rapid cellular proliferation. In particular, his laboratory develops a unifying theory regarding the role of the transcription factor E2f in pathological contexts such as cancer and inflammatory reactions. His long-term goal is to identify novel therapeutic strategies to harness proliferation and limit the accumulation of pathological cell populations, such as tumorigenic and pro-inflammatory cells.

APPOINTMENTS

2021–present: Associate Professor, Lankenau Institute for Medical Research
2012–2021: Assistant Professor and Principal Investigator, University of Pennsylvania and Children’s Hospital of Philadelphia

Contact

viatourp@mlhs.org
484.476.8513

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Education

Postdoctoral Fellowship, Evolution/Cancer Biology

Stanford University School of Medicine

PhD, Pharmaceutical Sciences

University of Liege, Belgium

MS, Pharmaceutical Sciences

University of Liege, Belgium

PharmD

University of Liege, Belgium

Awards & Honors

HONORS, AWARDS, CITATIONS

2021: RO1, NCI (CA-251397)
2016–2021: American Cancer Society Research Scholar Grant
2013–2014: WW Smith Scholar Award
2006–2009: Human Frontier Science Program (HFSP) Long-Term Postdoctoral Fellowship
2005–2007: European Molecular Biology Organization (EMBO) Long-Term Postdoctoral Fellowship

Publications

Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies. Windmueller R, Leach JP, … Viatour P, et al. Cell Rep. 2020 Mar 3;30(9):3105-3116.e4.
Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs. Mastio J, Condamine T, … Viatour P, et al. J Exp Med. 2019 Sep 2;216(9):2150-2169.
Promotion of growth factor signaling as a critical function of β-catenin during HCC progression. Kim E, … Viatour P. Nat Commun. 2019 Apr 23;10(1):1909.
Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. Kim E, Cheng Y, … Viatour P. J Exp Med. 2017 Jul 3;214(7):1901-1912.
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Tarangelo A, Lo N, … Viatour P. Nat Commun. 2015 Dec 7;6:10028. doi: 10.1038/ncomms10028.
Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. Garfin PM, Min D, … Viatour P. J Exp Med. 2013 Jun 3;210(6):1087-97.